Dichloromethane → 3-(4-(Methylsulfonyl)phenyl)-1,2,4-thiadiazol-5-amine

HRID 300528Notes

Reaction equation

HRID 300528 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[n:12][s:13][c:14]([NH:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[n:15]2)[cH:9][cH:10]1.[Cl:39][CH2:40][Cl:41].[F:32][C:33]([F:34])([F:35])[C:36]([OH:37])=[O:38].[c:24]1([O:25][CH3:26])[cH:27][cH:28][cH:29][cH:30][cH:31]1>>[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[n:12][s:13][c:14]([NH2:16])[n:15]2)[cH:9][cH:10]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 68743050Tert-butyl 3-(4-(methylsulfonyl)phenyl)-1,2,4-thiadiazol-5-ylcarbamate

Product 1

HCID 337802353-(4-(Methylsulfonyl)phenyl)-1,2,4-thiadiazol-5-amine

Sources & evidence

ORD record
ord-49389457a02a420d9201863af84e6571
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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