Hydrochloric Acid → 3-(1-Benzyl-piperidin-4-ylamino)-propan-1-ol

HRID 301256Notes

Reaction equation

HRID 301256 reaction equation
[C:20]([O:21][BH-:22]([O:23][C:24](=[O:25])[CH3:26])[O:27][C:28](=[O:29])[CH3:30])(=[O:31])[CH3:32].[CH2:37]([Cl:38])[Cl:39].[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[N:13]1[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]1.[ClH:34].[NH2:1][CH2:2][CH2:3][CH2:4][OH:5].[Na+:33].[Na+:36].[OH-:35]>>[NH:1]([CH2:2][CH2:3][CH2:4][OH:5])[CH:16]1[CH2:15][CH2:14][N:13]([CH2:6][c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[CH2:18][CH2:17]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 961HydroxideHCID 6344DichloromethaneHCID 90863-Amino-1-propanolHCID 192201-Benzyl-4-piperidoneHCID 2724942Triacetoxyborohydride

Product 1

HCID 31534663-(1-Benzyl-piperidin-4-ylamino)-propan-1-ol

Sources & evidence

ORD record
ord-eb07198f6f54469fb7a7125620f3be30
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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