Tetrahydrofuran → 6-Benzyloxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)phenyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester
Reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[O:14][c:15]1[cH:16][c:17]2[c:22]([cH:23][cH:24]1)[CH:21]([c:25]1[cH:26][cH:27][c:28]([O:31][CH2:32][CH2:33][N:34]3[CH2:35][CH2:36][CH2:37][CH2:38]3)[cH:29][cH:30]1)[NH:20][CH2:19][CH2:18]2.[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[Cl:1][C:2](=[O:3])[O:4][CH2:5][CH3:6]>>[C:2](=[O:3])([O:4][CH2:5][CH3:6])[N:20]1[CH2:19][CH2:18][c:17]2[cH:16][c:15]([O:14][CH2:7][c:8]3[cH:9][cH:10][cH:11][cH:12][cH:13]3)[cH:24][cH:23][c:22]2[CH:21]1[c:25]1[cH:26][cH:27][c:28]([O:31][CH2:32][CH2:33][N:34]2[CH2:35][CH2:36][CH2:37][CH2:38]2)[cH:29][cH:30]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-6235b36575df4b48aa156dd89265759c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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