Ammonia → 6-Chloro-2-(4-fluorophenyl)-3,4'-bipyridine-5-carbonitrile

HRID 302093Notes

Reaction equation

HRID 302093 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([OH:22])[c:11]([C:20]#[N:21])[cH:12][c:13]2-[c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[cH:6][cH:7]1.[NH3:28].[O:29]=[CH:30][N:31]([CH3:32])[CH3:33].[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([Cl:25])[c:11]([C:20]#[N:21])[cH:12][c:13]2-[c:14]2[cH:15][cH:16][n:17][cH:18][cH:19]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 222AmmoniaHCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 178509481HCID 178509481, compound

Product 1

HCID 859950346-Chloro-2-(4-fluorophenyl)-3,4'-bipyridine-5-carbonitrile

Sources & evidence

ORD record
ord-93e393cc2b0c496fb588dc810dc88420
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…