2-Butenedioic acid → 4-Amino-4-[1-(4-chlorophenyl)cyclobutyl]-2-methylbutan-2-ol
Reaction equation
[Al+3:21].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:12]([CH2:13][C:14]([CH3:15])([CH3:16])[OH:17])=[N:18][OH:19])[CH2:9][CH2:10][CH2:11]2)[cH:6][cH:7]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22].[Na+:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH-:34].[OH2:41].[OH:26][C:27]([CH:28]=[CH:29][C:30](=[O:31])[OH:32])=[O:33]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([CH:12]([CH2:13][C:14]([CH3:15])([CH3:16])[OH:17])[NH2:18])[CH2:9][CH2:10][CH2:11]2)[cH:6][cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-ee26e92bed1040ab93d29bfcce523651
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…