反应详情

The product of step b) (2.6 g, 5.2 mmol) in CH2Cl2 (25 ml) and trifluoroacetic acid (TFA) (75 ml) was stirred at 220C for 16 hours. Next, the solvent was evaporated and toluene (50 ml) was added and subsequently evaporated in vacuo at 40° C. to remove residual TFA. The crude subtitle product was used without further purification.

1. customNext, the solvent was evaporated
2. additiontoluene (50 ml) was added
3. customsubsequently evaporated in vacuo at 40° C.
4. customto remove residual TFA
5. customThe crude subtitle product was used without further purification