Tetrahydrofuran → HCID 58694695, compound

HRID 302569Notes

Reaction equation

[Al+3:35].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[CH:16]3[CH2:17][CH2:18][N:19]([c:22]4[c:23]5[c:24]([n:25][cH:26][n:27]4)[nH:28][cH:29][c:30]5[CH3:31])[CH2:20][CH2:21]3)[cH:10][cH:11][cH:12]2)[cH:32][cH:33]1.[H-:34].[H-:37].[H-:38].[H-:39].[Li+:36]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][CH2:14][CH:16]3[CH2:17][CH2:18][N:19]([c:22]4[c:23]5[c:24]([n:25][cH:26][n:27]4)[nH:28][cH:29][c:30]5[CH3:31])[CH2:20][CH2:21]3)[cH:10][cH:11][cH:12]2)[cH:32][cH:33]1

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 117192531-(5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid [3-(4-fluoro-phenoxy)-phenyl]-amide

Product 1

HCID 58694695HCID 58694695, compound

Sources & evidence

ORD record: ord-bbff76bf9d7e406b89e5f8bc37a74ae4
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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