Hydrochloric Acid → 2-{6,7-dimethyl-4-[5-methyl-2-(2H-1,2,3-triazol-2-yl)benzoyl]-1,4-diazepan-1-yl}-6-fluoroquinazoline
Reaction equation
[C:44](=[O:45])([O-:46])[O-:47].[CH3:2][CH:3]1[NH:4][CH2:5][CH2:6][N:7]([C:11]([c:12]2[c:13](-[n:19]3[n:20][cH:21][cH:22][n:23]3)[cH:14][cH:15][c:16]([CH3:18])[cH:17]2)=[O:24])[CH2:8][CH:9]1[CH3:10].[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[CH3:50][c:51]1[cH:52][cH:53][cH:54][cH:55][cH:56]1.[Cl:25][c:26]1[n:27][c:28]2[cH:29][cH:30][c:31]([F:36])[cH:32][c:33]2[cH:34][n:35]1.[ClH:1].[K+:48].[K+:49]>>[CH3:2][CH:3]1[N:4]([c:26]2[n:27][c:28]3[cH:29][cH:30][c:31]([F:36])[cH:32][c:33]3[cH:34][n:35]2)[CH2:5][CH2:6][N:7]([C:11]([c:12]2[c:13](-[n:19]3[n:20][cH:21][cH:22][n:23]3)[cH:14][cH:15][c:16]([CH3:18])[cH:17]2)=[O:24])[CH2:8][CH:9]1[CH3:10]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-753f784edf5741f88b8c03ac913791b4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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