Dimethylformamide → 4-Chloro-6-(1-imidazolyl)quinazoline

HRID 303411Notes

Reaction equation

[O:17]=[CH:18][N:19]([CH3:20])[CH3:21].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26].[n:1]1(-[c:6]2[cH:7][c:8]3[c:9](=[O:16])[nH:10][cH:11][n:12][c:13]3[cH:14][cH:15]2)[cH:2][n:3][cH:4][cH:5]1>>[n:1]1(-[c:6]2[cH:7][c:8]3[c:9]([Cl:24])[n:10][cH:11][n:12][c:13]3[cH:14][cH:15]2)[cH:2][n:3][cH:4][cH:5]1

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 24813Phosphorus oxychloride

HCID 1358228196-(1-Imidazolyl)-3,4-dihydroquinazolin-4-one

Product 1

HCID 218478354-Chloro-6-(1-imidazolyl)quinazoline

Sources & evidence

ORD record: ord-7f097ecca17f4965afa1912c2e7dfb81
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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