Hydrochloric Acid → 2-(3,4,5,6-Tetrahydro-2H-[1,4']bipyridyl-4-ylcarbamoyl)-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid methyl ester

HRID 304535Notes

Reaction equation

HRID 304535 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]2[c:9]([n:10]1)[cH:11][c:12]([C:14](=[O:15])[OH:16])[nH:13]2.[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[Cl:32][CH2:33][Cl:34].[ClH:17].[ClH:18].[N:19]1([c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[CH2:20][CH2:21][CH:22]([NH2:25])[CH2:23][CH2:24]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][c:8]2[c:9]([n:10]1)[cH:11][c:12]([C:14](=[O:16])[NH:25][CH:22]1[CH2:21][CH2:20][N:19]([c:26]3[cH:27][cH:28][n:29][cH:30][cH:31]3)[CH2:24][CH2:23]1)[nH:13]2

Participants

6

Reactant 5

HCID 313Hydrochloric Acid2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 189186081-(Pyridin-4-yl)piperidin-4-amineHCID 692267105-(methoxycarbonyl)-1H-pyrrolo(3,2-b)pyridine-2-carboxylic acid

Product 1

HCID 692278212-(3,4,5,6-Tetrahydro-2H-[1,4']bipyridyl-4-ylcarbamoyl)-1H-pyrrolo[3,2-b]pyridine-5-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-431559184e404dec92bb94cda5d1055c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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