Tetrahydrofuran → 3-(Dibenzylamino)-2,2-difluoropropan-1-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH2:9][C:10]([C:11](=[O:12])[O:13][CH2:14][CH3:15])([F:16])[F:17])[CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1.[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:25][CH:26]([CH2:27][AlH:28][CH2:29][CH:30]([CH3:31])[CH3:32])[CH3:33]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH2:9][C:10]([CH2:11][OH:12])([F:16])[F:17])[CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1Participants
4
Sources & evidence
- ORD record
- ord-3377da76caf147869bc8f4fc52351bd9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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