Acetone → (RS)-1-Benzenesulfonyl-3-benzyl-4-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-imidazolidin-2-one

HRID 305129Notes

Reaction equation

HRID 305129 reaction equation
[Br:32][CH2:33][c:34]1[cH:35][cH:36][cH:37][cH:38][cH:39]1.[C:40](=[O:41])([O-:42])[O-:43].[C:46](=[O:47])([O-:48])[O-:49].[CH3:52][C:53](=[O:54])[CH3:55].[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[K+:44].[K+:45].[Na+:50].[Na+:51].[c:1]1([S:7](=[O:8])(=[O:9])[N:10]2[C:11](=[O:31])[NH:12][CH:13]([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][N:20]([c:23]4[c:24]([CH3:30])[cH:25][cH:26][c:27]([CH3:29])[cH:28]4)[CH2:21][CH2:22]3)[CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[N:10]2[C:11](=[O:31])[N:12]([CH2:33][c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[CH:13]([C:15](=[O:16])[N:17]3[CH2:18][CH2:19][N:20]([c:23]4[c:24]([CH3:30])[cH:25][cH:26][c:27]([CH3:29])[cH:28]4)[CH2:21][CH2:22]3)[CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

8

Reactant 7

HCID 180AcetoneHCID 813Potassium Cation2×HCID 923Sodium ion2×HCID 7498Benzyl BromideHCID 8857Ethyl AcetateHCID 19660Carbonate Ion2×HCID 67141102HCID 67141102, compound

Product 1

HCID 25028838(RS)-1-Benzenesulfonyl-3-benzyl-4-[4-(2,5-dimethyl-phenyl)-piperazine-1-carbonyl]-imidazolidin-2-one

Sources & evidence

ORD record
ord-158d6f22c405416b8ca760c81e85b437
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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