Tetrahydrofuran → 3-Dimethylamino-1-(4-nitrobenzoyl)pyrrolidine

HRID 305268Notes

Reaction equation

HRID 305268 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:22][N:23]([CH:24]1[CH2:25][NH:26][CH2:27][CH2:28]1)[CH3:29].[CH:13]([N:14]([CH:15]([CH3:16])[CH3:17])[CH2:18][CH3:19])([CH3:20])[CH3:21].[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([C:8](=[O:9])[Cl:10])[cH:11][cH:12]1>>[N+:1](=[O:2])([O-:3])[c:4]1[cH:5][cH:6][c:7]([C:8](=[O:9])[N:26]2[CH2:25][CH:24]([N:23]([CH3:22])[CH3:29])[CH2:28][CH2:27]2)[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 85024-Nitrobenzoyl chlorideHCID 81531DiisopropylethylamineHCID 27585193-(Dimethylamino)pyrrolidine

Product 1

HCID 225675623-Dimethylamino-1-(4-nitrobenzoyl)pyrrolidine

Sources & evidence

ORD record
ord-aaaaf6740d3d4928956c957d29cdf0ce
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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