Sodium ion → 1-[5-(2-Fluoro-5-{[4-(trifluoromethyl)pyrimidin-2-yl]amino}phenyl)-1,3-thiazol-2-yl]cyclobutanol
Reaction equation
[Br:34][c:35]1[cH:36][n:37][c:38]([C:40]2([OH:44])[CH2:41][CH2:42][CH2:43]2)[s:39]1.[CH3:50][CH2:51][O:52][C:53](=[O:54])[CH3:55].[F:1][c:2]1[c:3]([B:19]2[O:20][C:21]([CH3:22])([CH3:23])[C:24]([CH3:25])([CH3:26])[O:27]2)[cH:4][c:5]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[n:14]2)[cH:6][cH:7]1.[Na+:28].[Na+:29].[O-:30][C:31](=[O:32])[O-:33].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[F:1][c:2]1[c:3](-[c:35]2[cH:36][n:37][c:38]([C:40]3([OH:44])[CH2:41][CH2:42][CH2:43]3)[s:39]2)[cH:4][c:5]([NH:8][c:9]2[n:10][cH:11][cH:12][c:13]([C:15]([F:16])([F:17])[F:18])[n:14]2)[cH:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f1e337a146a440a3bea9ec652d18110a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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