Sodium ion → Tert-butyl 4-[2-(3,3-difluorocyclopentyl)-2-hydroxy-2-phenylacetyl]oxypiperidine-1-carboxylate
Reaction equation
[C:19]([c:20]1[nH:21][cH:22][cH:23][n:24]1)([c:25]1[nH:26][cH:27][cH:28][n:29]1)=[O:30].[CH3:47][N:48]([CH3:49])[CH:50]=[O:51].[CH3:52][CH2:53][O:54][C:55](=[O:56])[CH3:57].[F:1][C:2]1([F:18])[CH2:3][CH:4]([C:7]([C:8](=[O:9])[OH:10])([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[OH:17])[CH2:5][CH2:6]1.[H-:45].[Na+:46].[OH:31][CH:32]1[CH2:33][CH2:34][N:35]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:36][CH2:37]1>>[F:1][C:2]1([F:18])[CH2:3][CH:4]([C:7]([C:8](=[O:9])[O:10][CH:32]2[CH2:33][CH2:34][N:35]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:36][CH2:37]2)([c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[OH:17])[CH2:5][CH2:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-92827ef735c44b53aa2d1a96c6744c7d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…