Dimethylformamide → 4-nitro-1H-pyrazole-3-carboxylic acid (2-amino-4-methoxy-phenyl)-amide

HRID 306640Notes

Reaction equation

HRID 306640 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([NH2:10])[c:6]([NH2:9])[cH:7][cH:8]1.[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[Cl:33][C:34]([C:35]([Cl:36])=[O:37])=[O:38].[Cl:39][CH2:40][Cl:41].[N+:11](=[O:12])([O-:13])[c:14]1[c:15]([C:19](=[O:20])[Cl:21])[n:16][nH:17][cH:18]1.[N+:22]([c:23]1[c:24]([C:25]([OH:26])=[O:27])[n:28][nH:29][cH:30]1)([O-:31])=[O:32]>>[CH3:1][O:2][c:3]1[cH:4][c:5]([NH2:10])[c:6]([NH:9][C:19]([c:15]2[c:14]([N+:11](=[O:12])[O-:13])[cH:18][nH:17][n:16]2)=[O:20])[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 1534044-Methoxy-o-phenylenediamineHCID 178521133HCID 178521133, compoundHCID 178524956HCID 178524956, compound

Product 1

HCID 1784923544-nitro-1H-pyrazole-3-carboxylic acid (2-amino-4-methoxy-phenyl)-amide

Sources & evidence

ORD record
ord-aa78d90917f14a45acf943e33c6d45e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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