Potassium Cation → tert-butyl 1-[4-chloro-6-(4-morpholinyl)-2-pyrimidinyl]-2-(difluoromethyl)-4-methoxy-1H-benzimidazol-6-ylcarbamate
Reaction equation
[CH3:46][CH2:47][O:48][C:49]([CH3:50])=[O:51].[Cl:23][c:24]1[n:25][c:26]([Cl:36])[cH:27][c:28]([N:30]2[CH2:31][CH2:32][O:33][CH2:34][CH2:35]2)[n:29]1.[Cl:43][CH2:44][Cl:45].[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([nH:7]1)[cH:8][c:9]([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[cH:10][c:11]2[O:12][CH3:13])[F:22].[K+:37].[K+:38].[O-:39][C:40]([O-:41])=[O:42].[O:52]=[CH:53][N:54]([CH3:55])[CH3:56].[OH2:57]>>[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:24]1[n:25][c:26]([Cl:36])[cH:27][c:28]([N:30]3[CH2:31][CH2:32][O:33][CH2:34][CH2:35]3)[n:29]1)[cH:8][c:9]([NH:14][C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[cH:10][c:11]2[O:12][CH3:13])[F:22]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-725a164aaeba468795310ef20f4db934
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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