Water → 5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-N-(3-(dimethylamino)propyl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamide
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:8])[c:9]1[c:10](=[O:27])[n:11](-[c:17]2[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]2)[c:12]([CH3:16])[c:13]([I:15])[cH:14]1)[CH3:28].[CH3:29][C:30]1([CH3:31])[C:32]([CH3:33])([CH3:34])[O:35][B:36]([c:37]2[cH:38][cH:39][n:40][n:41]2-[c:42]2[cH:43][cH:44][c:45]([C:46]#[N:47])[cH:48][cH:49]2)[O:50]1.[CH3:51][N:52]([CH3:53])[CH:54]=[O:55].[CH:57]([OH:58])([CH3:59])[CH3:60].[OH2:56]>>[CH3:1][N:2]([CH2:3][CH2:4][CH2:5][NH:6][C:7](=[O:8])[c:9]1[c:10](=[O:27])[n:11](-[c:17]2[cH:18][c:19]([C:23]([F:24])([F:25])[F:26])[cH:20][cH:21][cH:22]2)[c:12]([CH3:16])[c:13](-[c:37]2[cH:38][cH:39][n:40][n:41]2-[c:42]2[cH:43][cH:44][c:45]([C:46]#[N:47])[cH:48][cH:49]2)[cH:14]1)[CH3:28]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-775a0926d38e4e82bae386295f0fb251
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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