Pyridine → N-(6-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)pyridin-3-yl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide
Reaction equation
[CH2:37]([P:38](=[O:39])([OH:40])[OH:41])[CH2:42][CH3:43].[CH3:50][CH:51]1[CH2:52][CH2:53][CH2:54][O:55]1.[CH3:56][CH2:57][O:58][C:59](=[O:60])[CH3:61].[CH:19]12[CH2:20][CH2:21][CH:22]([CH2:23][CH2:24]1)[N:25]2[c:26]1[cH:27][cH:28][c:29]([NH2:36])[c:30]([C:32]([F:33])([F:34])[F:35])[n:31]1.[O:1]=[c:2]1[c:3]([C:16](=[O:17])[OH:18])[cH:4][nH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([C:12]([F:13])([F:14])[F:15])[c:11]12.[cH:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1>>[O:1]=[c:2]1[c:3]([C:16](=[O:18])[NH:36][c:29]2[cH:28][cH:27][c:26]([N:25]3[CH:19]4[CH2:20][CH2:21][CH:22]3[CH2:23][CH2:24]4)[n:31][c:30]2[C:32]([F:33])([F:34])[F:35])[cH:4][nH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([C:12]([F:13])([F:14])[F:15])[c:11]12Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9049c76f032844d393dece7cf0386d89
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…