Hydrochloric Acid → 6-Bromo-4-(2-(tetrahydro-2H-pyran-4-yl)ethyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one

HRID 307197Notes

Reaction equation

HRID 307197 reaction equation
[Br:1][CH2:2][C:3](=[O:4])[NH:5][c:6]1[n:7][cH:8][c:9]([Br:13])[n:10][c:11]1[Br:12].[CH:24]([N:25]([CH:26]([CH3:27])[CH3:28])[CH2:29][CH3:30])([CH3:31])[CH3:32].[ClH:14].[O:15]1[CH2:16][CH2:17][CH:18]([CH2:21][CH2:22][NH2:23])[CH2:19][CH2:20]1>>[CH2:2]1[C:3](=[O:4])[NH:5][c:6]2[n:7][cH:8][c:9]([Br:13])[n:10][c:11]2[N:23]1[CH2:22][CH2:21][CH:18]1[CH2:17][CH2:16][O:15][CH2:20][CH2:19]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 81531DiisopropylethylamineHCID 27731982-(Oxan-4-yl)ethan-1-amineHCID 582983072-bromo-N-(3,5-dibromopyrazin-2-yl)acetamide

Product 1

HCID 715670836-Bromo-4-(2-(tetrahydro-2H-pyran-4-yl)ethyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one

Sources & evidence

ORD record
ord-3c13e8a16a284ce3a6f66d22914b5f82
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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