Dimethylformamide → HCID 67352954, compound

HRID 308303Notes

Reaction equation

HRID 308303 reaction equation
[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:46][N:47]([C:48]([N:49]([CH3:50])[CH3:51])=[N+:52]1[c:53]2[c:54]([n:55][cH:56][cH:57][cH:58]2)[N+:59]([O-:60])=[N:61]1)[CH3:62].[CH3:63][C:64]([CH3:65])([CH3:66])[O:67][C:68](=[O:69])[N:70]1[CH2:71][CH2:72][CH:73]([NH2:76])[CH2:74][CH2:75]1.[CH3:80][N:81]([CH3:82])[CH:83]=[O:84].[CH:1]1([N:5]2[c:6]3[c:7]([cH:16][n:17][c:18]([NH:20][c:21]4[c:22]([O:30][CH3:31])[cH:23][c:24]([C:25](=[O:26])[OH:27])[cH:28][cH:29]4)[n:19]3)[N:8]([CH3:15])[C:9](=[O:14])[C:10]([F:12])([F:13])[CH2:11]2)[CH2:2][CH2:3][CH2:4]1.[Cl:77][CH2:78][Cl:79].[P-:39]([F:40])([F:41])([F:42])([F:43])([F:44])[F:45]>>[CH:1]1([N:5]2[c:6]3[c:7]([cH:16][n:17][c:18]([NH:20][c:21]4[c:22]([O:30][CH3:31])[cH:23][c:24]([C:25](=[O:26])[NH:76][CH:73]5[CH2:72][CH2:71][N:70]([C:68]([O:67][C:64]([CH3:63])([CH3:65])[CH3:66])=[O:69])[CH2:75][CH2:74]5)[cH:28][cH:29]4)[n:19]3)[N:8]([CH3:15])[C:9](=[O:14])[C:10]([F:12])([F:13])[CH2:11]2)[CH2:2][CH2:3][CH2:4]1

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 12682914-Amino-1-Boc-piperidineHCID 580150754-(9-cyclobutyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-3-methoxy-benzoic acidHCID 178484291HCID 178484291, compound

Product 1

HCID 67352954HCID 67352954, compound

Sources & evidence

ORD record
ord-747b0bd055dc4332a0afe87ba104729e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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