Trifluoroacetic acid → (3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidine-3-carboxylic acid
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][O:2][CH2:3][N:4]([CH2:5][Si:6]([CH3:7])([CH3:8])[CH3:9])[CH2:10][c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[CH3:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH3:48].[Cl:17][c:18]1[cH:19][c:20]([CH:25]=[CH:26][C:27](=[O:28])[OH:29])[cH:21][cH:22][c:23]1[Cl:24].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[CH2:3]1[N:4]([CH2:10][c:11]2[cH:12][cH:13][cH:14][cH:15][cH:16]2)[CH2:5][CH:26]([C:27](=[O:28])[OH:29])[CH:25]1[c:20]1[cH:19][c:18]([Cl:17])[c:23]([Cl:24])[cH:22][cH:21]1Participants
6
Sources & evidence
- ORD record
- ord-dbb825cfe89847e394fe495553aa0ad4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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