Dimethylformamide → tert-butyl N-[1-(4-bromophenyl)-4-[3-[4-chloro-1-(3-methoxypropyl)benzimidazol-2-yl]piperidin-1-yl]-4-oxobutan-2-yl]carbamate

HRID 308498Notes

Reaction equation

HRID 308498 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([CH2:29][CH:30]([CH2:31][C:32](=[O:33])[OH:34])[NH:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[cH:27][cH:28]1.[CH3:43][N:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49]1.[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[n:7]([CH2:17][CH2:18][CH2:19][O:20][CH3:21])[c:8]([CH:11]3[CH2:12][NH:13][CH2:14][CH2:15][CH2:16]3)[n:9][c:10]12.[O:74]=[CH:75][N:76]([CH3:77])[CH3:78].[P-:50]([F:51])([F:52])([F:53])([F:54])([F:55])[F:56].[n:57]1([O:58][C:59]([N:60]([CH3:61])[CH3:62])=[N+:63]([CH3:64])[CH3:65])[c:66]2[n:67][cH:68][cH:69][cH:70][c:71]2[n:72][n:73]1>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[n:7]([CH2:17][CH2:18][CH2:19][O:20][CH3:21])[c:8]([CH:11]3[CH2:12][N:13]([C:32]([CH2:31][CH:30]([CH2:29][c:26]4[cH:25][cH:24][c:23]([Br:22])[cH:28][cH:27]4)[NH:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:33])[CH2:14][CH2:15][CH2:16]3)[n:9][c:10]12

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 53397991Boc-3-amino-4-(4-bromo-phenyl)-butyric acidHCID 667859224-Chloro-1-(3-methoxypropyl)-2-piperidin-3-ylbenzimidazole

Product 1

HCID 77191058tert-butyl N-[1-(4-bromophenyl)-4-[3-[4-chloro-1-(3-methoxypropyl)benzimidazol-2-yl]piperidin-1-yl]-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-13318bfe028b42ff9fec959a4ff9c126
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…