1,2-Dichloroethane → bis(1,1-dimethylethyl) (4-{[({4-chloro-3-[(3-chloro-5-cyanophenyl)oxy]-2-fluorophenyl}methyl)amino]carbonyl}-1H-imidazol-2-yl)imidodicarbonate
Reaction equation
[C:58](=[O:59])([OH:60])[O-:61].[CH2:1]([Cl:2])[CH2:3][Cl:4].[CH3:35][C:36]([CH3:37])([CH3:38])[O:39][C:40](=[O:41])[N:42]([c:43]1[nH:44][cH:45][c:46]([C:48](=[O:49])[OH:50])[n:47]1)[C:51](=[O:52])[O:53][C:54]([CH3:55])([CH3:56])[CH3:57].[NH2:15][CH2:16][c:17]1[c:18]([F:34])[c:19]([O:24][c:25]2[cH:26][c:27]([C:28]#[N:29])[cH:30][c:31]([Cl:33])[cH:32]2)[c:20]([Cl:23])[cH:21][cH:22]1.[Na+:62].[O:63]=[CH:64][N:65]([CH3:66])[CH3:67].[OH:5][n:6]1[c:7]2[c:8]([cH:9][cH:10][cH:11][cH:12]2)[n:13][n:14]1>>[NH:15]([CH2:16][c:17]1[c:18]([F:34])[c:19]([O:24][c:25]2[cH:26][c:27]([C:28]#[N:29])[cH:30][c:31]([Cl:33])[cH:32]2)[c:20]([Cl:23])[cH:21][cH:22]1)[C:48]([c:46]1[cH:45][nH:44][c:43]([N:42]([C:40]([O:39][C:36]([CH3:35])([CH3:37])[CH3:38])=[O:41])[C:51](=[O:52])[O:53][C:54]([CH3:55])([CH3:56])[CH3:57])[n:47]1)=[O:49]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-84a206a0e38c47aba9ff8d97495caa35
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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