Potassium Cation → methyl 4-[1-methyl-4-(trifluoromethyl)-1H-pyrazol-5-yl]-2-thiophenecarboxylate

HRID 308682Notes

Reaction equation

HRID 308682 reaction equation
[CH2:19]([Si:20]([CH2:21][CH3:26])([C:22]([F:23])([F:24])[F:25])[CH2:27][CH3:28])[CH3:29].[CH3:35][N:36]([CH3:37])[P:38]([N:39]([CH3:40])[CH3:41])([N:42]([CH3:43])[CH3:44])=[O:45].[Cu:46][I:47].[F-:17].[I:1][c:2]1[cH:3][n:4][n:5]([CH3:16])[c:6]1-[c:7]1[cH:8][c:9]([C:12](=[O:13])[O:14][CH3:15])[s:10][cH:11]1.[K+:18].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[c:2]1([C:22]([F:23])([F:24])[F:25])[cH:3][n:4][n:5]([CH3:16])[c:6]1-[c:7]1[cH:8][c:9]([C:12](=[O:13])[O:14][CH3:15])[s:10][cH:11]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 6228DimethylformamideHCID 12679HexamethylphosphoramideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 28179Fluoride IonHCID 4204914Triethyl(trifluoromethyl)silaneHCID 57826893methyl 4-(4-iodo-1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylate

Product 1

HCID 57826913methyl 4-[1-methyl-4-(trifluoromethyl)-1H-pyrazol-5-yl]-2-thiophenecarboxylate

Sources & evidence

ORD record
ord-70c8b1db7e904b6c81ee5f34b0261ec3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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