Tetrahydrofuran → trans-4-{4-[Methyl(3-phenylpropyl)amino]cyclohexyl}phenol

HRID 308786Notes

Reaction equation

HRID 308786 reaction equation
[Al+3:29].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:1][O:2][C:3]([N:4]([CH2:5][CH2:6][CH2:7][c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[CH:14]1[CH2:15][CH2:16][CH:17]([c:20]2[cH:21][cH:22][c:23]([OH:26])[cH:24][cH:25]2)[CH2:18][CH2:19]1)=[O:27].[H-:28].[H-:31].[H-:32].[H-:33].[Li+:30]>>[CH3:3][N:4]([CH2:5][CH2:6][CH2:7][c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[CH:14]1[CH2:15][CH2:16][CH:17]([c:20]2[cH:21][cH:22][c:23]([OH:26])[cH:24][cH:25]2)[CH2:18][CH2:19]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 10133584HCID 10133584, compound

Product 1

HCID 9862008trans-4-{4-[Methyl(3-phenylpropyl)amino]cyclohexyl}phenol

Sources & evidence

ORD record
ord-dccf1c6b9ed04049aa478a0f4594fb5d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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