Tetrahydrofuran → 5-(5-Methyl-2-phenyl-4-oxazolylmethoxy)-3-pyridylmethanol

HRID 308792Notes

Reaction equation

HRID 308792 reaction equation
[Al+3:26].[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:15]2[cH:16][c:17]([C:21](=[O:22])[O:23][CH3:24])[cH:18][n:19][cH:20]2)[n:4][c:5](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[o:6]1.[H-:25].[H-:28].[H-:29].[H-:30].[Li+:27].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:15]2[cH:16][c:17]([CH2:21][OH:22])[cH:18][n:19][cH:20]2)[n:4][c:5](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[o:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 17861341Methyl 5-(5-methyl-2-phenyl-4-oxazolyl)methoxy-3-pyridinecarboxylate

Product 1

HCID 178612255-(5-Methyl-2-phenyl-4-oxazolylmethoxy)-3-pyridylmethanol

Sources & evidence

ORD record
ord-e1dbbe73e78149f48448fc8f7a0ebbf9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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