Hydrochloric Acid → 2-{2-(Methoxycarbonyl)methoxyphenoxy}-5-fluoro-4-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]nitrobenzene

HRID 309000Notes

Reaction equation

HRID 309000 reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[ClH:44].[F:14][c:15]1[c:16]([N+:35](=[O:36])[O-:37])[cH:17][c:18]([F:34])[c:19](-[n:21]2[c:22](=[O:33])[n:23]([CH3:32])[c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][c:26]2=[O:27])[cH:20]1.[K+:42].[K+:43].[OH:1][c:2]1[c:3]([O:4][CH2:5][C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11][cH:12][cH:13]1>>[O:1]([c:2]1[c:3]([O:4][CH2:5][C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11][cH:12][cH:13]1)[c:15]1[c:16]([N+:35](=[O:36])[O-:37])[cH:17][c:18]([F:34])[c:19](-[n:21]2[c:22](=[O:33])[n:23]([CH3:32])[c:24]([C:28]([F:29])([F:30])[F:31])[cH:25][c:26]2=[O:27])[cH:20]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 23202292-(Methoxycarbonyl)methoxyphenolHCID 121155092,5-Difluoro-4-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]nitrobenzene

Product 1

HCID 187592902-{2-(Methoxycarbonyl)methoxyphenoxy}-5-fluoro-4-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl]nitrobenzene

Sources & evidence

ORD record
ord-3a256550120748c7931527db5d604ffa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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