Ammonium → Methyl 3-(1-hydroxyethyl)-5-[3-methoxy-4-(phenylmethoxycarbonylamino)piperidin-1-yl]thiophene-2-carboxylate
Reaction equation
[Br-:1].[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH2:4]([c:5]1[cH:6][cH:7][cH:8][cH:9][cH:10]1)[O:11][C:12](=[O:13])[NH:14][CH:15]1[CH:16]([O:32][CH3:33])[CH2:17][N:18]([c:21]2[cH:22][c:23]([CH:30]=[O:31])[c:24]([C:26](=[O:27])[O:28][CH3:29])[s:25]2)[CH2:19][CH2:20]1.[CH3:2][Mg+:3].[Cl-:34].[NH4+:35]>>[CH3:2][CH:30]([c:23]1[cH:22][c:21]([N:18]2[CH2:17][CH:16]([O:32][CH3:33])[CH:15]([NH:14][C:12]([O:11][CH2:4][c:5]3[cH:6][cH:7][cH:8][cH:9][cH:10]3)=[O:13])[CH2:20][CH2:19]2)[s:25][c:24]1[C:26](=[O:27])[O:28][CH3:29])[OH:31]Participants
7
Sources & evidence
- ORD record
- ord-07b65fd94ef944539155f78709ee008d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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