Hydrochloric Acid → tert-Butyl 4-((1H-benzo[d]imidazol-2-yl)amino)piperidine-1-carboxylate

HRID 309145Notes

Reaction equation

HRID 309145 reaction equation
[C:1]([O:2][C:3](=[O:4])[n:8]1[c:9]([NH:17][CH:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22][CH2:23]2)[n:10][c:11]2[c:12]1[cH:13][cH:14][cH:15][cH:16]2)([CH3:5])([CH3:6])[CH3:7].[ClH:39].[Na+:38].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1.[OH-:37].[OH2:31].[OH2:40]>>[nH:8]1[c:9]([NH:17][CH:18]2[CH2:19][CH2:20][N:21]([C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:22][CH2:23]2)[n:10][c:11]2[c:12]1[cH:13][cH:14][cH:15][cH:16]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962Water2×HCID 8028TetrahydrofuranHCID 22009170(1-(t-butoxycarbonyl)-1H-benzimidazol-2-yl)(1-(t-butoxycarbonyl)piperidin-4-yl)amine

Product 1

HCID 22036999tert-Butyl 4-((1H-benzo[d]imidazol-2-yl)amino)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-db1b4f7d72d94f6ab2873ef07ec701ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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