Tetrahydrofuran → N-{4-[6-Cyano-7-(2-hydroxy-3-(piperidin-1-yl)propoxy)quinolin-4-yloxy]-2-fluorophenyl}-N'-(4-fluorophenyl)urea
Reaction equation
[C:7](#[N:8])[c:9]1[cH:10][c:11]2[c:12]([O:24][c:25]3[cH:26][c:27]([F:42])[c:28]([NH:31][C:32](=[O:33])[NH:34][c:35]4[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]4)[cH:29][cH:30]3)[cH:13][cH:14][n:15][c:16]2[cH:17][c:18]1[O:19][CH2:20][CH:21]1[O:22][CH2:23]1.[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1>>[CH2:1]1[CH2:2][CH2:3][N:4]([CH2:23][CH:21]([CH2:20][O:19][c:18]2[c:9]([C:7]#[N:8])[cH:10][c:11]3[c:12]([O:24][c:25]4[cH:26][c:27]([F:42])[c:28]([NH:31][C:32](=[O:33])[NH:34][c:35]5[cH:36][cH:37][c:38]([F:41])[cH:39][cH:40]5)[cH:29][cH:30]4)[cH:13][cH:14][n:15][c:16]3[cH:17]2)[OH:22])[CH2:5][CH2:6]1Participants
4
Sources & evidence
- ORD record
- ord-fcb8e46ecea3468aac4189163266ccbb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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