Toluene → 2,4-Difluoro-3-(7-pyridin-4-yl-2,3-dihydro-pyrazolo[5,1-b]thiazol-6-yl)phenylamine
Reaction equation
[CH2:1]([N:8]([CH2:2][c:3]1[cH:4][cH:5][cH:6][cH:7][cH:31]1)[c:9]1[c:10]([F:30])[c:11](-[c:16]2[n:17][n:18]3[c:19]([c:23]2-[c:24]2[cH:25][cH:26][n:27][cH:28][cH:29]2)[S:20][CH2:21][CH2:22]3)[c:12]([F:15])[cH:13][cH:14]1)[c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1.[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH3:53][CH2:54][O:55][C:56](=[O:57])[CH3:58].[F:38][C:39]([F:40])([F:41])[S:42]([OH:43])(=[O:44])=[O:45]>>[NH2:8][c:9]1[c:10]([F:30])[c:11](-[c:16]2[n:17][n:18]3[c:19]([c:23]2-[c:24]2[cH:25][cH:26][n:27][cH:28][cH:29]2)[S:20][CH2:21][CH2:22]3)[c:12]([F:15])[cH:13][cH:14]1Participants
5
Sources & evidence
- ORD record
- ord-c2a368c6ac6844ce819c90824b0d45a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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