Ammonium → 3-(2,2-difluoro-6-hydroxy-1,3-benzodioxol-5-yl)-3-hydroxy-1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1,3-dihydro-2H-indol-2-one

HRID 309791Notes

Reaction equation

HRID 309791 reaction equation
[CH:14]([Mg+:15])([CH3:16])[CH3:17].[Cl-:13].[Cl-:39].[F:18][C:19]([c:20]1[cH:21][cH:22][c:23]([CH2:25][N:26]2[C:27](=[O:36])[C:28](=[O:35])[c:29]3[cH:30][cH:31][cH:32][cH:33][c:34]32)[o:24]1)([F:37])[F:38].[F:1][C:2]1([F:12])[O:3][c:4]2[c:5]([cH:7][cH:8][c:9]([OH:11])[cH:10]2)[O:6]1.[NH4+:40].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[F:1][C:2]1([F:12])[O:3][c:4]2[c:5]([cH:7][c:8]([C:28]3([OH:35])[C:27](=[O:36])[N:26]([CH2:25][c:23]4[cH:22][cH:21][c:20]([C:19]([F:18])([F:37])[F:38])[o:24]4)[c:34]4[c:29]3[cH:30][cH:31][cH:32][cH:33]4)[c:9]([OH:11])[cH:10]2)[O:6]1

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312Chloride2×HCID 8028TetrahydrofuranHCID 673563422,2-Difluorobenzo[d][1,3]dioxol-5-olHCID 673564881-((5-(Trifluoromethyl)furan-2-yl)methyl)indoline-2,3-dioneHCID 178461726HCID 178461726, compound

Product 1

HCID 673577963-(2,2-difluoro-6-hydroxy-1,3-benzodioxol-5-yl)-3-hydroxy-1-{[5-(trifluoromethyl)furan-2-yl]methyl}-1,3-dihydro-2H-indol-2-one

Sources & evidence

ORD record
ord-29e51896bf6048d48c922f41f135ef28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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