Methanol → Ethyl 2-(5-fluorobenzofur-7-yl)acetate

HRID 310569Notes

Reaction equation

HRID 310569 reaction equation
[C:1]([O:2][CH:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[c:11]1[cH:12][c:13]([F:20])[cH:14][c:15]2[cH:16][cH:17][o:18][c:19]12)(=[O:3])[CH3:4].[CH3:21][N:22]([P:23]([N:24]([CH3:25])[CH3:26])([N:27]([CH3:28])[CH3:29])=[O:30])[CH3:31].[CH3:32][OH:33].[CH3:42][CH2:43][O:44][C:45](=[O:46])[CH3:47].[I-:39].[I-:41].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1.[Sm+2:40]>>[CH2:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[c:11]1[cH:12][c:13]([F:20])[cH:14][c:15]2[cH:16][cH:17][o:18][c:19]12

Participants

8

Reactant 7

HCID 887MethanolHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 12679HexamethylphosphoramideHCID 30165Iodide Ion2×HCID 22144811HCID 22144811, compoundHCID 178528036HCID 178528036, compound

Product 1

HCID 22144764Ethyl 2-(5-fluorobenzofur-7-yl)acetate

Sources & evidence

ORD record
ord-dd716b76a52943bf8626c36c30387c8e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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