Dimethylformamide → N-((4-fluoro-1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)-2-methyl-4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)benzamide

HRID 311487Notes

Reaction equation

HRID 311487 reaction equation
[CH3:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([C:11]2=[N:12][O:13][C:14]([C:16]([F:17])([F:18])[F:19])([c:20]3[cH:21][c:22]([Cl:28])[c:23]([Cl:27])[c:24]([Cl:26])[cH:25]3)[CH2:15]2)[cH:10]1.[CH:53]([N:54]([CH2:55][CH3:56])[CH:57]([CH3:58])[CH3:59])([CH3:60])[CH3:61].[NH2:62][CH2:63][c:64]1[cH:65][c:66]([F:76])[c:67]2[c:68]([cH:75]1)[B:69]([OH:74])[O:70][C:71]2([CH3:72])[CH3:73].[O:77]=[CH:78][N:79]([CH3:80])[CH3:81].[P-:29]([F:30])([F:31])([F:32])([F:33])([F:34])[F:35].[n:36]1([O:37][C:38]([N:39]([CH3:40])[CH3:41])=[N+:42]([CH3:43])[CH3:44])[c:45]2[cH:46][cH:47][cH:48][cH:49][c:50]2[n:51][n:52]1>>[CH3:1][c:2]1[c:3]([C:4](=[O:6])[NH:62][CH2:63][c:64]2[cH:65][c:66]([F:76])[c:67]3[c:68]([cH:75]2)[B:69]([OH:74])[O:70][C:71]3([CH3:72])[CH3:73])[cH:7][cH:8][c:9]([C:11]2=[N:12][O:13][C:14]([C:16]([F:17])([F:18])[F:19])([c:20]3[cH:21][c:22]([Cl:28])[c:23]([Cl:27])[c:24]([Cl:26])[cH:25]3)[CH2:15]2)[cH:10]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 866854502-Methyl-4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)benzoic acidHCID 866855046-(aminomethyl)-4-fluoro-3,3-dimethylbenzo[c][1,2]oxaborol-1(3H)-ol

Product 1

HCID 71576287N-((4-fluoro-1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)-2-methyl-4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)benzamide

Sources & evidence

ORD record
ord-317cf26288c44404ae179a98b3404057
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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