Tetrahydrofuran → 3,4-Difluoro-2-[[2-fluoro-4-(ethylthio)phenyl]amino]benzoic acid
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:25][Si:26]([N-:27][Si:28]([CH3:29])([CH3:30])[CH3:31])([CH3:32])[CH3:33].[F:13][c:14]1[c:15]([NH2:16])[cH:17][cH:18][c:19]([S:21][CH2:22][CH3:23])[cH:20]1.[F:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([F:12])[c:10]1[F:11].[Li+:24]>>[c:2]1([NH:16][c:15]2[c:14]([F:13])[cH:20][c:19]([S:21][CH2:22][CH3:23])[cH:18][cH:17]2)[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][c:9]([F:12])[c:10]1[F:11]Participants
6
Sources & evidence
- ORD record
- ord-00d6cedf1eff43f982e6b30484d38da8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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