Chloride → 5-Chloro-6-(quinolin-3-yloxy)pyridin-3-amine

HRID 311987Notes

Reaction equation

HRID 311987 reaction equation
[CH3:25][CH2:26][O:27][C:28](=[O:29])[CH3:30].[Cl-:24].[Cl:1][c:2]1[c:3]([O:11][c:12]2[cH:13][n:14][c:15]3[cH:16][cH:17][cH:18][cH:19][c:20]3[cH:21]2)[n:4][cH:5][c:6]([N+:8]([O-:9])=[O:10])[cH:7]1.[OH2:22].[OH2:23]>>[Cl:1][c:2]1[c:3]([O:11][c:12]2[cH:13][n:14][c:15]3[cH:16][cH:17][cH:18][cH:19][c:20]3[cH:21]2)[n:4][cH:5][c:6]([NH2:8])[cH:7]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 962Water2×HCID 8857Ethyl AcetateHCID 68793755HCID 68793755, compound

Product 1

HCID 687907985-Chloro-6-(quinolin-3-yloxy)pyridin-3-amine

Sources & evidence

ORD record
ord-403121bd6d4947d19c8f13b8a50b01a2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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