Water → 1-[Bis(4-fluorophenyl)methyl]-2-formyl-4,6-dimethyl-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
Reaction equation
[CH3:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:47][N:48]([CH:49]=[O:50])[CH3:51].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:19][c:20]1[cH:21][cH:22][c:23]([CH:26]([n:27]2[cH:28][c:29]([C:38]#[N:39])[c:30]3[c:31]2[n:32][c:33]([CH3:37])[cH:34][c:35]3[CH3:36])[c:40]2[cH:41][cH:42][c:43]([F:46])[cH:44][cH:45]2)[cH:24][cH:25]1.[Li:8][CH2:9][CH2:10][CH2:11][CH3:12].[O:52]1[CH2:53][CH2:54][CH2:55][CH2:56]1.[OH2:57]>>[F:19][c:20]1[cH:21][cH:22][c:23]([CH:26]([n:27]2[c:28]([CH:49]=[O:50])[c:29]([C:38]#[N:39])[c:30]3[c:31]2[n:32][c:33]([CH3:37])[cH:34][c:35]3[CH3:36])[c:40]2[cH:41][cH:42][c:43]([F:46])[cH:44][cH:45]2)[cH:24][cH:25]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-a8ff90999cfe427e96dea363996aa58e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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