Ammonium → 1-Benzyl-4-[2-fluoro-5-(trifluoromethyl)benzyl]piperidin-4-ol
Reaction equation
[Br:2][CH2:3][c:4]1[c:5]([F:14])[cH:6][cH:7][c:8]([C:10]([F:11])([F:12])[F:13])[cH:9]1.[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[N:22]1[CH2:23][CH2:24][C:25](=[O:28])[CH2:26][CH2:27]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[Cl-:29].[I:1].[NH4+:30]>>[CH2:3]([c:4]1[c:5]([F:14])[cH:6][cH:7][c:8]([C:10]([F:11])([F:12])[F:13])[cH:9]1)[C:25]1([OH:28])[CH2:24][CH2:23][N:22]([CH2:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:27][CH2:26]1Participants
7
Sources & evidence
- ORD record
- ord-b436e8fbc5be4fecaef8cc260836cbe5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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