Hydrochloric Acid → HCID 75985946, compound

HRID 312761Notes

Reaction equation

[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][CH2:7][C:8](=[O:9])[c:10]1[cH:11][cH:12][c:13]([NH:16][C:17](=[O:18])[CH:19]2[CH:20]([c:39]3[c:40]([F:46])[c:41]([Cl:45])[cH:42][cH:43][cH:44]3)[C:21]3([C:22](=[O:31])[NH:23][c:24]4[cH:25][c:26]([Cl:30])[cH:27][cH:28][c:29]43)[CH:32]([CH2:34][C:35]([CH3:36])([CH3:37])[CH3:38])[NH:33]2)[cH:14][cH:15]1)([CH3:5])([CH3:47])[CH3:48].[ClH:49].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1>>[OH:6][CH2:7][C:8](=[O:9])[c:10]1[cH:11][cH:12][c:13]([NH:16][C:17](=[O:18])[CH:19]2[CH:20]([c:39]3[c:40]([F:46])[c:41]([Cl:45])[cH:42][cH:43][cH:44]3)[C:21]3([C:22](=[O:31])[NH:23][c:24]4[cH:25][c:26]([Cl:30])[cH:27][cH:28][c:29]43)[CH:32]([CH2:34][C:35]([CH3:36])([CH3:37])[CH3:38])[NH:33]2)[cH:14][cH:15]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 8028Tetrahydrofuran

HCID 76741099rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid {4-[2-(tert-butyl-dimethyl-silanyloxy)-acetyl]-phenyl}-amide

Product 1

HCID 75985946HCID 75985946, compound

Sources & evidence

ORD record: ord-c6856b2943aa45fb8f422c4c3fce3d07
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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