Tetrahydrofuran → tert-butyl 3-((2-chloro-9-methyl-6-morpholino-9H-purin-8-yl)methylene)azetidine-1-carboxylate
Reaction equation
[C:33](=[O:34])([O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[N:40]1[CH2:41][C:42](=[O:44])[CH2:43]1.[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[CH3:26][CH:27]([N-:28][CH:29]([CH3:30])[CH3:31])[CH3:32].[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[n:6][c:7]([CH2:12][P:13](=[O:14])([O:15][CH3:16])[O:17][CH3:18])[n:8]([CH3:11])[c:9]2[n:10]1.[Li+:25]>>[Cl:1][c:2]1[n:3][c:4]([N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[c:5]2[n:6][c:7]([CH:12]=[C:42]3[CH2:41][N:40]([C:33](=[O:34])[O:35][C:36]([CH3:37])([CH3:38])[CH3:39])[CH2:43]3)[n:8]([CH3:11])[c:9]2[n:10]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-bb92bf17b39248efbee88b0a9e00dc92
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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