Tetrahydrofuran → 1-Boc-3-hydroxypiperidine

HRID 313006Notes

Reaction equation

HRID 313006 reaction equation
[C:8]([CH3:9])([CH3:10])([CH3:11])[O:12][C:13]([O:14][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:15].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[OH:1][CH:2]1[CH2:3][NH:4][CH2:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][N:4]([C:13]([O:12][C:8]([CH3:9])([CH3:10])[CH3:11])=[O:14])[CH2:5][CH2:6][CH2:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 232933-HydroxypiperidineHCID 10219638Carbonic acid, bis(1,1-dimethylethyl) ester

Product 1

HCID 5456991-Boc-3-hydroxypiperidine

Sources & evidence

ORD record
ord-2b7c22e4694d49fd9eb2f5cb0f04e4cf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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