Dichloromethane → 2-{4-Fluoro-4-[2-(2-isopropyl-2H-[1,2,4]triazol-3-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulen-8-yl]-piperidin-1-yl}-N,N-dimethyl-acetamide
Reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][C:11]([c:14]2[cH:15][c:16]3[c:17]([cH:34][cH:35]2)-[c:18]2[n:19][c:20](-[c:26]4[n:27]([CH:31]([CH3:32])[CH3:33])[n:28][cH:29][n:30]4)[s:21][c:22]2[CH2:23][CH2:24][O:25]3)([F:36])[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[Cl:51][CH2:52][C:53](=[O:54])[N:55]([CH3:56])[CH3:57].[Cl:58][CH2:59][Cl:60].[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43]>>[N:8]1([CH2:52][C:53](=[O:54])[N:55]([CH3:56])[CH3:57])[CH2:9][CH2:10][C:11]([c:14]2[cH:15][c:16]3[c:17]([cH:34][cH:35]2)-[c:18]2[n:19][c:20](-[c:26]4[n:27]([CH:31]([CH3:32])[CH3:33])[n:28][cH:29][n:30]4)[s:21][c:22]2[CH2:23][CH2:24][O:25]3)([F:36])[CH2:12][CH2:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-b4d6b7efdef34142b35ea40875a710dd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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