Water → [7-(3-Methanesulfonyl-pyridin-2-yl)-5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidin-4-yl]-(4-trifluoromethyl-phenyl)-amine
Reaction equation
[CH3:43][N:44]([CH3:45])[C:46](=[O:47])[CH3:48].[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl:22][c:23]1[n:24][cH:25][cH:26][cH:27][c:28]1[S:29](=[O:30])(=[O:31])[CH3:32].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([NH:9][c:10]2[c:11]3[c:12]([n:13][cH:14][n:15]2)[CH2:16][NH:17][CH2:18][CH2:19]3)[cH:7][cH:8]1)([F:20])[F:21].[O:49]1[CH2:50][CH2:51][O:52][CH2:53][CH2:54]1.[OH2:42]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([NH:9][c:10]2[c:11]3[c:12]([n:13][cH:14][n:15]2)[CH2:16][N:17]([c:23]2[n:24][cH:25][cH:26][cH:27][c:28]2[S:29](=[O:30])(=[O:31])[CH3:32])[CH2:18][CH2:19]3)[cH:7][cH:8]1)([F:20])[F:21]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-4c9483becda243048d13913ed4c62353
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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