Dichloromethane → 2-(5-bromo-2-fluorophenyl)-1-[tert-butyl(dimethyl)silyl]oxy-N-[(4-methoxyphenyl)methyl]propan-2-amine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([F:22])[c:6]([C:8]([CH2:9][OH:10])([CH3:11])[NH:12][CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[cH:7]1.[C:30]([CH3:31])([CH3:32])([CH3:33])[Si:34]([Cl:35])([CH3:36])[CH3:37].[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[CH3:41][N:42]([CH3:43])[c:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1.[Cl:38][CH2:39][Cl:40]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([F:22])[c:6]([C:8]([CH2:9][O:10][Si:34]([C:30]([CH3:31])([CH3:32])[CH3:33])([CH3:36])[CH3:37])([CH3:11])[NH:12][CH2:13][c:14]2[cH:15][cH:16][c:17]([O:20][CH3:21])[cH:18][cH:19]2)[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e4f6bf2aa5dd462898a3f429562af5ff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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