Hydrochloric Acid → (9-(9-Hydroxynonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanone

HRID 314376Notes

Reaction equation

HRID 314376 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11].[CH3:13][c:14]1[s:15][cH:16][c:17]([C:19](=[O:20])[N:21]2[CH2:22][CH2:23][O:24][C:25]3([CH2:26]2)[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]3)[n:18]1.[CH3:32][CH2:33][N:34]([CH2:35][CH3:36])[CH2:37][CH3:38].[CH3:39][C:40]#[N:41].[ClH:12]>>[CH2:2]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][OH:11])[N:29]1[CH2:28][CH2:27][C:25]2([O:24][CH2:23][CH2:22][N:21]([C:19]([c:17]3[cH:16][s:15][c:14]([CH3:13])[n:18]3)=[O:20])[CH2:26]2)[CH2:31][CH2:30]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6342AcetonitrileHCID 8471TriethylamineHCID 1087001-Nonanol, 9-bromo-HCID 57989231(2-Methyl-1,3-thiazol-4-yl)-(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)methanone

Product 1

HCID 46240299(9-(9-Hydroxynonyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)(2-methylthiazol-4-yl)methanone

Sources & evidence

ORD record
ord-9bc38eb573bc43c28278466442ef99c7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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