Isopropanol → tert-butyl {2-[4-({3-methyl-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}carbamate
Reaction equation
[CH3:21][c:22]1[cH:23][c:24]([NH2:25])[cH:26][cH:27][c:28]1[O:29][c:30]1[cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[cH:33][cH:34][cH:35]1.[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[CH:40]([OH:41])([CH3:42])[CH3:43].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH2:11][CH2:12][NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20]>>[c:2]1([NH:25][c:24]2[cH:23][c:22]([CH3:21])[c:28]([O:29][c:30]3[cH:31][c:32]([C:36]([F:37])([F:38])[F:39])[cH:33][cH:34][cH:35]3)[cH:27][cH:26]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH2:11][CH2:12][NH:13][C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b4bf33fc8ce74f15b3d5338751a900a1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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