Tetrahydrofuran → 2-(2-Furoyl)-3-oxo-1,2-benzisothiazoline-6-carboxylic acid methyl ester

HRID 315496Notes

Reaction equation

HRID 315496 reaction equation
[CH3:9][O:10][C:11](=[O:12])[c:13]1[cH:14][c:15]2[c:16]([c:17](=[O:20])[nH:18][s:19]2)[cH:21][cH:22]1.[Na:23].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1.[o:1]1[c:2]([C:6](=[O:7])[Cl:8])[cH:3][cH:4][cH:5]1>>[o:1]1[c:2]([C:6](=[O:7])[n:18]2[c:17](=[O:20])[c:16]3[c:15]([cH:14][c:13]([C:11]([O:10][CH3:9])=[O:12])[cH:22][cH:21]3)[s:19]2)[cH:3][cH:4][cH:5]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 682422-Furancarbonyl chlorideHCID 5360545SodiumHCID 19076707Methyl 3-Hydroxybenzo[d]isothiazole-6-carboxylate

Product 1

HCID 543616282-(2-Furoyl)-3-oxo-1,2-benzisothiazoline-6-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-e8a40544078a4f098b359fdd2ec67762
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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