Tetrahydrofuran → 4-[4-(2-Oxa-5-azabicyclo[2.2.1]heptan-5-yl)-1-(2,2,2-trifluoroethyl)pyrazolo[5,4-d]pyrimidin-6-yl]aniline

HRID 315593Notes

Reaction equation

HRID 315593 reaction equation
[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[N+:1]([O-:2])(=[O:3])[c:4]1[cH:5][cH:6][c:7](-[c:10]2[n:11][c:12]([N:24]3[CH:25]4[CH2:26][O:27][CH:28]([CH2:29]3)[CH2:30]4)[c:13]3[c:14]([n:15]2)[n:16]([CH2:19][C:20]([F:21])([F:22])[F:23])[n:17][cH:18]3)[cH:8][cH:9]1.[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1>>[NH2:1][c:4]1[cH:5][cH:6][c:7](-[c:10]2[n:11][c:12]([N:24]3[CH:25]4[CH2:26][O:27][CH:28]([CH2:29]3)[CH2:30]4)[c:13]3[c:14]([n:15]2)[n:16]([CH2:19][C:20]([F:21])([F:22])[F:23])[n:17][cH:18]3)[cH:8][cH:9]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 178526547HCID 178526547, compound

Product 1

HCID 771494084-[4-(2-Oxa-5-azabicyclo[2.2.1]heptan-5-yl)-1-(2,2,2-trifluoroethyl)pyrazolo[5,4-d]pyrimidin-6-yl]aniline

Sources & evidence

ORD record
ord-ce6cafa6aa6148249bc937f374e81fef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…