Chloride → Imatinib amine

HRID 316258Notes

Reaction equation

HRID 316258 reaction equation
[CH3:1][c:2]1[c:3]([NH:11][c:12]2[n:13][cH:14][cH:15][c:16](-[c:18]3[cH:19][n:20][cH:21][cH:22][cH:23]3)[n:17]2)[cH:4][c:5]([N+:8]([O-:9])=[O:10])[cH:6][cH:7]1.[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[CH3:33][CH2:34][OH:35].[Cl-:26].[OH2:24].[OH2:25]>>[CH3:1][c:2]1[c:3]([NH:11][c:12]2[n:13][cH:14][cH:15][c:16](-[c:18]3[cH:19][n:20][cH:21][cH:22][cH:23]3)[n:17]2)[cH:4][c:5]([NH2:8])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 702EthanolHCID 962Water2×HCID 8857Ethyl AcetateHCID 106861492-(2-Methyl-5-nitroanilino)-4-(3-pyridyl)pyrimidine

Product 1

HCID 9965429Imatinib amine

Sources & evidence

ORD record
ord-761683c7bba14277a1c9dc390a23a119
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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